Today I was able to watch a KGS Plus lecture live. I usually end up replaying them afterwards, which isn't nearly as much fun.
The lecture by Guo Juan was about joseki with emphasis on their proper use. I was pleased to watch this lecture given my newfound interest in joseki study. Guo Juan had given another lecture on joseki a couple weeks ago, which I had missed and plan to go back and watch soon.
One of the things she said today is that early on we should learn 10 joseki, then increase that to 20, and that by the time we are 1 dan we should know at least 50 joseki. That sounds reasonable to me.
In applying joseki she suggested that you know the final outcome(s) of the joseki you are considering, and to imagine those outcomes with the current board position. If none of the outcomes are pleasing to you, then it is time to make up your own move to deviate from joseki. I like that thinking.
She emphasized that it is not necessary to try to learn all joseki, but to learn the basic ones. She has audio go lessons on joseki, and also recommended taking a joseki book and picking the simple variations to learn. That's pretty much what I intend to do.